Drug Repurposing Candidates for Triple-Negative Breast Cancer
Discover (after iteration 6) — find something NEW that iteration 6 did not establish: a pattern, formula, conjecture or effect that no published work reports. Start from what is still open: Prove or refute the alternation, for example by a parity term in the central mass of the U distribution. Extend the DP beyond n=30; Fix one convention and state a conjecture. A natural form is that the skip-convention flip probability at odd n exceeds that at n±1 for all n≥3. Test it at n=31..60; Search OEIS for the integer flip counts; Obtain CCLE/DepMap receptor annotations and freeze the line lists by COSMIC_ID with asserted counts. Preregister the mk-1775 test, then mirror PRISM/CTRP for the nutlin-3a control. Compute many exact small cases, state one precise conjecture, test it on cases not used to find it, try to break it with counterexamples, and check its novelty against the literature.
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